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 COURSE SCHEDULE & RESOURCES 2019-2020: Ms. Margaret Bahe
Tuesday and Thursday Labs

BioInFocusImage Bio in focus SG AP lab manual
biology collage
Jump to Specific Units by clicking below:
Fall Semester Spring Semester
  • Resouces Canvas for JBS
  • Course Overview Binder pages 1-164
  • Unit 1: Chemistry of Life, especially water; Apply to Seed Germination & Xylem Transport Binder pages 65 - 104
  • Unit 2: Cell Structure & Membrane Transport; Apply to Phloem Transport Binder pages 105 - 160
  • Unit 3: Metabolism & Enzymes; Apply to Human Digestion Binder pages 161 - 194
  • Unit 4: Energy Process - Respiration; Apply to Gas Exchange Systems Binder pages 195 - 242
  • Unit 5: Energy Process - Photosynthesis; Apply to adaptations for Environmental conditions Binder pages 243 - 280
  • Unit 6: Cell Division & Regulation of Division; Binder pages 281 - 340
  • Unit 7: Cell Signaling & Communication; Apply to Hormones & Immunity Binder pages 341 - 362
  • Fall Final Exam Binder Pages 363 - 374
  • Unit 8: DNA, Protein Synthesis; Apply to Biotechnology Binder pages 1 - 128
  • Unit 9: Genetics & Inheritance Binder pages 129 - 166
  • Unit 10: Natural Selection & The Origin & Diversity Life Binder pages 167 - 296
  • Unit 11: Interactions: Sensory & Response Systems, Behavior & Ecology Binder pages 297 - 386
  • Review Separate Binder TBA(Coming in late April)

Textbook Campbell's Biology in Focus, 3rd Edition, published in 2019. Sections indicated from the syllabus are from this text. Students need not bring their texts to class unless specifically asked to do so. Students can also access the text online. Use the text as a resource to explain the topics discussed in class and lab.

Study Guide &
Reading Guides

Study guide to accompany Campbell's Biology in Focus, 1st edition. Specific sections from each chapter will be noted on the syllabus. In addition, students will find a wealth of study aids on the website that accompanies Campbell's Biology in Focus.
Lab Manual AP Biology Investigative Labs (published by the College Board) plus numerous addtional labs described in handouts in the class binder. Updates to the first edition are available here. The HHMI guide to statistics is extremely helpful.
Lab Results &Notebook Students will keep a record of their laboratory work in their notebook/binder, including all raw data collection and documentation of their laboratory investigations. Students will also be writing formal lab reports and data analysis on most of their investigations.



Students will use the syllabus below for both daily and long term asssignments. Due dates and specific details may be adjusted during class. Reading assignments should be completed before class, although "pop quizzes" will never be given. Some students find reading more helpful after having heard discussion of the topics. The textbook should be used as just one of many available resources to help clarify concepts. Often a short (5-15 minute) video clip or two is offered to present the content in addition to the text.
Binder Students will receive both a Fall Binder, a Spring Binder and a Review binder. These binders should be brought to class and lab everyday. They contain diagrams, handouts, worksheets, lab descriptions, practice problems, and other useful materials for the efficient flow of class. Students should add their own notes directly to this binder. Binder Pages as PDFs
Reading About Biology

 UNIT #1

 1: THE CHEMISTRY OF LIFE: Binder Pages: Unit1

Week 1: August 22 - 23: school begins (Two Days)
Lab 2

Quick Introduction to course Themes ppt (may not be used) & The Four Big Ideas;
Marshmallow Challenge (Reference)
Asking Scientific Questions: The Spitting/Jumping Fish; Hypotheses & Predictions
Discuss experimental design for Seed Germination Experiment (Set up on Monday) (See Binder pg. 69-70)
How to write a strong research report
How to Write a Research Hypothesis (from NABT)

Welcome Back!!
Here is where the assignment for this day would be listed.
If you stumble here in the summer, feel free to peruse chapter #1
Class 3

Chemistry for Biology (Use the periodic table Binder pg. 67-68); Emphasis here is on types of chemical bonds & electronegativity
Chem Review ppt

Text 2.1 - 2.4** or Watch chemistry Background for Biology (kind of dull but helpful) (Organization items listed on the assignment for the weekend.)

**Nearly everything we talk discuss in Chemistry today should be review since you have had an entire year of chemistry. A couple of concepts will be indispencible, so concentrate on isotopes, energy levels, valence shell electrons, electronegativity & types of bonding.
Week 2: August 26 - 30
Class 1

Lab Set Up: Scientific Method: Design an Experiment: Seed Germination (Binder 69-70); new greenhouse is available


Text 1.1 (Skim), 1.2 (Skim), 1.3 (Read)** (See below)
Read Science Policies Binder pg. 3; Register for Campbell's website (Binder pg 4);
Sign the Safety contract (pg. 5)
Find our class website;
Download the AP Bio essays (see toppage of this web) to your computer.
Insert Dividers into binder (See above box for pages # on units) Look thru Binder 8-64 just to see what's there. Optional: Don't let this happen to you! I'm here to help!
**Use your text as a reference. Much of the Biology content of the course will be discussed in class and your text will serve to help explain that content in another way. You may read the content before or after class; you will never have a "pop quiz" on a night's reading but sometimes you will be expected to be ready to discuss the reading in classs.
Lab 1

Lab Activities: Water's Properties; (Binder pg. 79-80)
Water Properties ppt;
How to write a research hypothesis from NABT
Lab: Check Seeds

Two new Bozeman videos: Ocean Acidification and Coral Bleaching

Text 2.5; Nice short summary here
on the properties of water. Complete Chemistry Review (Binder 75-77) Answers to Chem Review - check yours;
OPTIONAL: Watch Bozeman's Water - A Polar Molecule
Class 2 Application: Water Transport in Plants: check Seeds
Skill: Interpreting a Scatter Plot with Regression Line: Text pg. 41 (Binder page 89): Carbonate ion concentration ad Calcification Rate of a Coral Reef
Text 29.5 - Pay particular attention to how the properties of water are used in the process of water transport & Watch Plant Transport: Xylem & Phloem (Med. Animations) (5.5 min)
Lab 2 Introduce and Practice using EXCEL for data tables and graphs -
Use seed data; (See Introduction to Data Analysis Binder 71 and 91+)
Text 3.1**(Reading ahead about Carbon)
Watch "Making a Line Graph in Excel" (6.5 minutes - use as future resource)
**I will ask you to memorize the functional groups in figure 3.6: name, formula (from Textbook pg. 48) and properties conferred (from class); you could make some flashcards to help you learn these.
Class 3

Carbon & Functional Groups (Use Binder pg. 83) Carbon ppt
Use organic molecules models All Organic Molecules ppt
Discuss writing the first essay

Text 3.2 - 3.3

Week 3: Sept 2 - 6 (4 DAYS --  No Mon. Labor Day)
Class 1

No School - Labor Day

No School
Lab 1 AP Lab #11: (Begin) Transpiration in Plants: Set up (Binder pg. 85+);
Input data into Google Spreadsheet (See your email)
Read AP Lab Manual pg. 135 - 137; Write Essay #129 on water (See below)
Essay #129: The unique properties (characteristics) of water make life possible on Earth.  Select three properties of water and:
a.  For each property, identify and define and explain it in terms of the physical/chemical nature of water.
b.  For each property, describe one example of how the property affects the functioning of living organisms
Class 2

Introduce Polymers; Carbohydrates (Binder diagrams pg. 95+and on)
Use organic molecules models All Organic Molecules ppt
Mass Plants

Watch Bozeman's Carbohydrates
Remember to work on your seed germination lab report

Lab 2

AP Lab #11: Measuring Stomate Densities
Put data into Google Spreadsheet
HHMI Guide to Statistics
can be helpful here
LAB: Use Excel to add error bars to the seed germination graphs. Print. Discuss evaluation of the data. Due next lab period.
Mass Plants

Text 29.6;
Watch video: Bozeman's Finding Stomata (4.5 minutes) and watch How Stomata Can Open & Close (1.5 min.)
Remember to work on your seed germination lab report
Class 3

Finish Carbohydrates (Binder pg. 95+) & Begin Lipids (Binder pg. 86+) All Organic Molecules ppt
Mass Plants; Bahe will mass over the weekend

Text 3.4 and/or watch Bozeman's Lipids;
Write answers to Stomate Questions (Handed out in class or link provided)
Remember to work on your seed germination lab report
Week 4: Sept. 9 - 13
Class 1

Finish Lipids; Begin discussion of protein structure (Binder 98+); build with toobers


Remember to work on your seed germination lab report - Due Tomorrow
Text 3.5
Watch Bozeman's Proteins;

Optional: Watch: Summary of What is a Protein? (3.5min) Includes some functional examples
Optional: Denaturation of proteins -

Optional: Want more information on exactly what SEM and 95% CI are? Try this 10 min. video: Standard Deviation & Standard Error of the Mean (very clear and straightforward)

Lab 1

AP Lab #11: Transpiration in Plants: Follow-up; (Binder pg.85+); Plant Structure & Transport (Binder 81-82);
Determine leaf surface area; calculate water loss per surface area unit; Discuss evaluation of data; all students will evaluate three questions.
Transport in Plants ppt

Optional: simulation for the effect of temperature on the rate of transpiration with a new technique to measure transpiration -

Complete Lab on Seed Germination (One data table & two graphs made with EXCEL with error bars on the bar graph; short conclusion - items #1-3 from Lab Report Discussion Binder p. 12) - Due TODAY
Useful videos:
How to add error bars to Excel graph (nice accent);
How to add error bars in Google Chart.
Lab 2

Complete proteins & organic molecules (Binder pg. 100+) All Organic Molecules ppt
Model protein structure with toober toys

Lab Skills: Using spreadsheets to do calculations, create data tables, calculate statistics, and draw graphs for transpiration lab. (Binder 85+); you should leave lab today with all data done for at least one question. (Final Transpiration Lab Report is due Monday Oct 1)

Useful Video: Adding Error Bars in Excel (2 min)
Intro to Statistics ppt

Practice identifying the organic molecules illustrated on Binder Page 103;
Watch Bozeman The Molecules of Life; reviews Carbon, Groups, & organics (10 min);
Look over unit objectives - What questions do you have?
Optional Statistics fun: Look at these Spurious Correlations
Optional/ Abssentees: Here is a good summary of protein structure by Dr. Dave: Protein Structure (11 min)

Class 3 TEST: Unit #1 (See essay question below)
Chapters: 1 , 2, 3, parts of 29 (29.5 - 29.6)
Prepare for TEST
Write Essay Question #
Test Essay 57. Discuss the biological importance of each of the following organic compounds in relation to cellular structure and function in plants and animals. Include how the structure of these molecules allows them to carry out these functions. a. Carbohydrates. b. Proteins c. Lipids. d. Nucleic acids {Comments: Ignore nucleic acids for now. Don't restrict yourself to only cellular structure & function. Do other levels too. The last sentence in italics is mine; it's not part of the original question.}
STUDY GUIDES Write the answers to the following in your study guide
Ch. 1:
Focus Questions: 1.6 - 1.7  Multiple Choice: 1-3, 5, 6
Ch. 2: Focus Questions: All except 2.12 Structure your knowledge:1, 3Multiple Choice: All except 22 and 43
Ch. 3: Focus Questions: All (write 3.9 to the left- include at least 8 links) except 3.10 and 3.11 (we will not study nucleic acids now) Structure your knowledge: 2, 3 & 4 (You will need a sheet of paper for #4) Matching All except 3 and 6 Multiple Choice: All except 6, 14, 22, and 24-26

Objectives for Unit #1
Working With Data: Feminization of Frogs, Testing Significance, Protein Structure

ESSAYS 149, 193,129, 199, 110, 35, 57, 110, 127, 152, 185,  31, 48a, 55a, 99, 109, 125, 134, 158, 175, 199, 212, 229
VIDEOS The videos section of the resurces provides links to videos that either are short snippets on individual concepts, or they are 10-15 minute presentations on a larger topic. Those done by Bozemen Science (by an AP Bio teacher named Paul Anderson) are the best. If you'd like to hear another point of view, listen to a presentation a second time, like to review orally, or need to make up a lesson becaue of an absence, then these Bozeman videos are for you. Peter Raven's site has numerous short animations on many topics we study.

Mr. Anderson (Bozeman Science) can walk you through
- Biological Molecules
- Molecules of Life
- Polymers
- Carbohydrates
- Lipids
- Proteins
- Water: A Polar Molecule
- Acids, Bases & pH
- Plant Nutrition and Transport
From 3D Medical Animations: (Great Visuals)
- Plant Transport in xylem and phloem

Need a little more on Protein structure? Check out Kristina Gremski's Proteins Part 1 and Proteins Part II.
Feeling weak on your chemistry? check out chemistry Background for Biology (by Gremski)
Kahn Academy has lots to offer for Chemistry Topics (Over 100!) You might like bonds, Periodic table, balancing equations, & pH

Statistics: Correlation is not Causation
Mr. Anderson teach some statistics: Chi-Square Test, Standard Deviation, Standard Error and Statistics for Science
Clear presentationof Standard Deviation & SEM
How to add error bars to Excel Graph (nice accent!)
Ted Talk: Marshmallow Challenge
A Professor uses the Archerfish for Asking Scientific Questions
FYI: Game/Puzzle on Protein Folding Video about the designer

 UNIT # 2


Week 5: sept. 16 - 20
Class 1

Return Tests
Intro to Cell Membrane Structure
Mechanisms of cell transport across membranes

Text 5.1 Work on Transpiration Lab: Make table for question 2 (the effect of your variable on one of the plant types); (table and graph for question 1 should already be completed) Due Thurs Oct 3

Lab 1 AP Lab #4: Diffusion & Cell Size; Diffusion & Solute Size; Cell Races; (Parts 1 & 2 - Binder pg. 109+)
Demo: Celery &Carrots; Demo Iodine & Starch
Introduce Parts 3 & 4 of Lab concerning Water Potential
Text 5.2
Watch Bozeman's The Cell Membrane (6.5 min)
Read & Bring AP Lab Manual Lab #4 Intro pg. 51 - 54
Work on Transpiration Lab: Make progress on graph for Plant Type #2; Due Thursday Oct. 3
RadioLab (NPR) has a fun and interesting segment analyzing why small cells like sperm and bacterium need special adaptations for movement. 5 minutes of interest - scroll down to the video at Comparing Sperm Whales To Sperm: A Swimming Contest
Class 2

Discuss Mechanisms for Transport Across Membranes (Use Binder page 121 - 129+- outline)
Membrane Structure & Function Modeling Diffusion ; Cell Membranes & Transport ppt

Text 5.3 - 5.5 Watch Bozeman's Transport Across Membranes (14 min) and Membrane Transport in Cells Symport, Antiport, Co-transport [3D Animation] (6 min)
Lab 2

AP Lab #4: Parts 3: Solute Concentration and Diffusion Rates; Determining Water Potential (Binder 112+); Set up Google Doc for AP Lab #4; share results
During the 30 min. wait time, discuss WATER POTENTIAL

Text 5.3** (Bozeman's video on Cell Membrane Structure & Cell Walls is quite good)
Complete AP Lab #4 parts 1 & 2 (Binder pages 109-111 - to be turned in Friday Sept. 28)
**This reading, Text 5.3, will make much more sense after today's lab.
Class 3

Share Data from Part 3: Solute Concentration and Diffusion Rates
Calculate the Percent Change in Mass (if not done in lab the previous day)

APPLICATIONS: Food Transport in Plants (Binder page 159) Transport in Plants ppt and Water Regulation (Osmoregulation in Fish (Binder 160) (See Bozeman Osmoregulation)

Text 29.7; Watch Phloem Loading (2.3 min);
Work on AP Lab #4 Parts 1, 2, & 3 (Membrane Models, Solute Molarity & Diffusion Rate Binder pg. 109-113 - Turned in Sept. 28) & Transpiration Lab - Make Data Table for comparing your two plant types (comparing transpiration rates of the experimentals for the two plant types); help available periods 2, 4, 5. (HINT: You've done the calculations for the two experimentals; just organize the two set of data into one data table in a separate sheet).

Week 6: Sept. 23 - 27 (Blue & Gold week)
Class 1

If needed, Finish Applications (Food Transport in plants (emphasize plasmodesmata, too)& Osmoregulation is Fish & Contractile Vacuoles in protists & Central Vacuoles in plants) of water potential
Importance of cholesterol to membrane flexibility
Begin Cell Structure & Function (Binder pg. 133+) Cell Structure ppt
Use cards to compare cells to factories

Text 4.1 - 4.4** (like videos? Try Bozeman's Cellular Organelles);
Work on Transpiration Lab - Make Graph(s) for comparing the two types of plants; include information on the two experimentals plus a bar graph comparing the stomate densities of the top and bottom of the leaves. (Due Oct. 3)
Help will be available periods 2, 4, 5, 6, and 9.

**You will need to memorize cell organelles, their structure (recognize in a diagram), and their functions. Start now making some flash cards -- remember -- you will benefit from making your own flashcards! Continue making flashcards with tomorrow night's reading.
Lab 1

AP Lab #4: Part 4: Set up Determining Water Potential (Binder 101+); Set up Google Doc for Part 4
LAB: If time, do Part 5: Plasmolysis in Plant (Red Onion & Elodea) cells (Binder pg. 117); if no time, complete on Thursday

Text 4.5-4.7;
Watch What is Plasmolysis (1 min. Med. Animations)
Work on conclusions for the Transpiration Lab (Due Oct 3); you will write one conclusion fo rthe big overarching question: What is the effect of your variable on transpiration? Address your two plant types in your conclusion.
OPTIONAL: (Like to preview today's lab? Try Bozeman's Osmosis Lab WalkThrough and Water Potential (Both for AP Lab #4 Part 4))

Class 2

Finish Cell Structure & Function (Binder 133+)

Text 5.4 - 5.5
Work on AP LAb #4 (109-117)
Work on your conclusion for your transspiration lab
Lab 2

Follow-up to Lab Part 4: Determine the Water Potential of Potato and Vegetables; Calculate percent change in mass; Share data in Google Doc; work on all parts of the lab - Due Tomorrow; time in class for working on this lab.
Practice Problems on Water Potential
LAB: If not yet completed, do Part 5: Plasmolysis in Plant (Red Onion & Elodea) cells (Binder pg. 117)

Practice Labeling typical Cells (Binder 137-138)
Finish up Transpiration Lab (Due Oct 3) by finishing your conclusion, three line graphs, one bar graph, and a data table for the three line graphs. Text 29.2 may be helpful with conclusion.
Class 3 Cell Structure & Function (Binder 137-138)
Try Practice sample water potential problems (Binder 139)

Text 29.2
Remember Bozeman's Water Potential video.
AP Lab #4: Complete All Parts, 1-5, of Lab Due Today (Binder pg. 109-117)

Week 7: SEPT. 30 - Oct. 4 (3 days - No Monday, Rosh Hashanah & NO CLASSES WED FOR SENIORS) (Bahe @ Drey LaND, Session 1, sun - wed.)
Class 1

No School - Rosh Hashanah Observance

No School
Lab 1

Lab: Cell Structure (Binder 141 - 150)
Make observations & Drawings of various plant, animal, protist & bacterial cells.

Try Water Potential Sample questions (Binder pg. 153+ #TBA) Answers will be posted here.
Class 2

No Classes for Seniors

Complete Transpiration Lab: DUE TOMORROW! Print before you come to class. Staple in the order of : Q1: Table, Graph for Ajuga, Q2: Table, Graph for plant Pachysandra, and Q3: Table, Graph Ajuga & Pachysandra compared, Bar graph of Stomate Densities, Conclusion .
Lab 2

Lab: Membranes and Temperature: Using a spectrophotometer to measure pigment leakages from red beet tissue. Share data in lab and discuss results.  (Binder pg. 119-120)
Return Lab #4 on Cell Membranes and Water Potential.

Transpiration Lab Due TODAY!
Try Water Potential Sample questions (Binder pg. 153+ #TBA) Answers will be posted here.
Class 3 Review
Try Practice sample water potential problems (Binder 153+)
Possible: Origins of cell compartmentalization

Look at unit objectives. Come with questions for your test.

Week 8: Oct. 7 - 11 (2 Days - Yom Kippur on Wednesday; no school Thurs or Fri - Report Writing)
Class 1

Test: Unit #2; Chapters 4 and 5 (not section 5.6)

Prepare for TEST
STUDY GUIDES Ch. 4: Focus Questions: 4.1 (b-d), 4.2, 4.4, 4.5, 4.6 (a-d) Structure your knowledge: 1 - 4 (Use just a short phrase to summarize the function of each for #2, ) Multiple Choice: All except 3, 14 - 16
Ch. 5: Focus Questions: 5.1 - 5.7, 5.9; for 5.3 make the list [We will parts of Ch. 5 later in another unit; don't cross them out] Structure your knowledge: 2 Multiple Choice: 1 - 18 (some of these are quite challenging)
Ch. 29: Focus Questions: 29.2, 29.9, 29.10, 29.11 Structure your knowledge: #4 only (Write on the bottomon page 215) Multiple Choice: 3, 4, 6, 7, 21, 22, 23, 24, 25

#137. Cells transport substances across their membranes.  Choose THREE of the following four types of cellular transport.

  • Osmosis
  • Active Transport
  • Facilitated Diffusion
  • Endocytosis
    For each of the Three transport types you choose,
    a)  describe the transport process and explain how the organization of cell membranes functions in the movement of specific molecules across membranes; and
    b)  explain the significance of each type of transport to a specific cell (you may use different cell types as examples.)
OTHERS Objectives for Unit #2
ESSAYS 1, 27, 41, 58, 70, 75, 94, 113, 117a, 127, 152, 137, 156, 156c, 168D, 170, 173, 177,

Mr. Anderson of Bozeman can help you with
- Cellular Organelles
- Compartmentalization,
- Cell Membrane Structure & Cell Walls,
- Transport Across Cell Membranes,
- SA/Vol Ratios.(Environmental Matter Exchange)
- Why are cells small?
- LAB: Diffusion Demo (How to Cut & Set up Potato cores)
- LAB: Water Potential - Discussion & Calculation
- Osmoregulation

You can try the Kahn Academy lectures for
- Parts of a Cell
- Diffusion & Osmosis
- Na+/K+ Pump

Take a tour of animal cell
Interactive from Learn Genetics: Cell Size & Scale
Youtube: Phloem Loading

 UNIT # 3

 3: METABOLISM & DIGESTION Binder Pages Unit 3

Lab 1

Return Tests
Lab: Measuring the Rate of Enzyme Catalyzed Reactions -
Identify catalase presence in various biological tissue
Learn technique to measure the rate of catalase reaction; choose a variable (Binder pg. 163+)

Text 6.4
Watch Bozeman's Enzymes (12 min)
Class 2

No School: Yom Kippur

No School

Lab 2

No School: Report Writing

No School
Class 3

No School: report Writing

No School
Week 9: Oct. 14 - 18 (Saturday is Blue & Gold Dance)
Class 1

Introduction to Metabolism, Thermodynamics & ATP (Binder pg. 169+) Metabolism, ATP & Enzymes ppt

Text 6.2 & 6.4 and/or watch Bozeman's ATP);
Do Watch Bozeman's Life Requires Energy for a big picture overview of energy & life;
(ABSENT TODAY? Try Energetics ppt (8.9MB) to review class)
Lab 1

Lab: Measuring the Rate of Enzyme Catalyzed Reaction - Run experiment; Making a Mini-Poster using the template (Binder pg. 167)

Text 6.1
Think about your design for a controlled procedure to answer your question about enzyme rates;
rewatch Bozeman's Enzymes .
Class 2 Gibbs Free Energy; Activation Energy & ATP (Binder pg. 170+) Metabolism, ATP & Enzymes ppt
Can use Binder pg. 179-182 chemical Reactions & Energy KEY POSTED HERE;

Text 6.3
Watch Bozeman's Gibbs Free Energy; Work on Lab Mini-Poster;
Bring (not do) Binder pages Chemical Reactions & Energy (Binder 179-182); we may work on this in class after discussion.
Lab 2

AP Lab #13: Experiment using Turnip Peroxidase (In lab manual) -- Learn technique (Also binder pg. 171+);
Design experiment for evaluating whether the peroxidase from various root tissues have the same optimal pH; share data in Google Doc

Work on Mini-Poster on Catalase Investigation;
Read AP Lab Manual pg. 153 - 156 and/or watch video (13 min) AP Lab #13: Enzyme Activity with Peroxidase
Class 3

Enzyme Regulation - Cofactors, Inhibition, Membrane Placement (Binder 177-178)

Text 6.5
Finish writing answers to Chemical Reactions & Energy (Binder pg. 179-182) and compare your thoughts to the Key;
Week 10: Oct. 21 - 25 (Fall Play - practices & Performances)
Class 1

APPLICATION: Digestive Enzymes in the Human System (Binder pg. 183+) The Digestive System ppt

Text 33.2 (Adaptations)
Complete Mini-Poster on Catalase Investigation;
Lab 1

APPLICATION: Adaptations in Digestive Systems, especially the human system (Binder pg. 183+)
Lots of YouTube videos on digestive adaptations. Digestion ppt

33.3 - 33.4** (Digestive Sytsems); Watch Bozeman's The Digestive System (10 min), concentrate on anatomy & enzymes;

**As you read, pay particular attention to adaptations that increase the efficiency for mechanical and chemical digestion as well as absorption. Interesting article: Can Gut Bacteria Explain Your Mood?
Class 2

Complete adaptations of Animal Adaptations to Digestion & Enzymes
(Herbivores v Carivores; Ruminants; Carnivorous plants)
Review for tests (PPC multiple choice questions, essay)
Overview of Cellular Respiration

Complete Mini-Poster on Catalase Investigation;
Complete Peroxidase Lab Follow-up (explained in class - Questions, Graphs & a conclusion table Binder pg. 175)
Lab 2 AP Lab #6: Design an experiment to Measure Rate of Cellular Respiration (For Gas Law review) (Binder pg. 199+) Lab Seed/ Invertebrate Respiration ppt Read & Bring AP Lab Manual pg. 71 - 72;
Watch Bozeman's Intro to Cellular Respiration Lab (Good Intro; alternate method is not our method, however); Label Binder pg. 183 (bottom); Write one paragraph to answer the digestive question below.

The digestive system ingests, digests, and absorbs nutrients. Identify and explain one specific example within the human digestive system that illustrates each of the following:
(A) an adaptation to increase surface area for absorption
(B) an adaptation to increase the surface area of a substrate for enzymatic attack
(C) an adaptation to protect the system lining from digesting itself

Class 1

Class 3

Note to Bahe: Moved Test form Fri to Monday

Return Tests
Intro/Overview to Cellular Respiration: Oxidation & Reduction; NAD+, ATP production; Mitochrondrial structure (Binder diagrams pg. 203+) Cell Respiration ppt

Complete Peroxidase Lab Follow-up (explained in class - Questions, Graphs & a conclusion table Binder pg. 175)
Text 7.1
Try Bozeman's Cellular Respiration. It will be helpful to watch again AFTER we have discussed the process.
Watch Bozeman's the Importance of Oxygen;

Optional: Animation of Cellular Resp. Stages (6 min)
**For respiration and photosynthesis, you do NOT need to memorize the process. You need to be able to read the diagrams and answer questions about the process. You are likely to be presented with the diagrams.

Class 3

Class 1

Moved rom Friday to Monday

TEST: Unit #3; Chapters: 6, 33 (parts 33.2 - 33.5)

Prepare for TEST
Essay #145 for the test (See Objectives)

STUDY GUIDES Ch. 6: Focus Questions: All Structure your knowledge: 1 and 2 (try to answer these in one short sentence each) Fill in the Blanks: 1-10 Multiple Choice: All
Ch. 33: Focus Questions: 33.4, 33.5, 33.6, [Don't cross out 33.8 - we will use later] Structure your knowledge: 1 Multiple Choice: 3, 6, 7, 8, 9, 10, 12, 14
TEST ESSAY Write Essay #145 outside of class and bring to the test. (See the end of your objectives; /the essay and it's associated graph is written there.).
OTHERS Objectives for Unit #3;
ESSAYS 26, 52, 81, 97, 123, 134, 145, 170, 185, 194, 202, 11, 49, 84, 90, 125, 154, 193, 199, 11, 49, 84, 90, 125, 154, 226

Mr. Anderson can talk you through...
- and overview of cellular energetics in general (respiration and photosynthesis)
- Gibbs free energy and why life requires it
- how matter cycles: the hidden part of cell respiration
- Enzymes
- the digestive system

National Geographic: the Digestive System (5 min - kind of gross but interesting video footage)
Iken Edu's Learn About Digestive System (Soothing English accent)

Kahn Academy will explain
- ATP and
- how ATP is hydrolyzed as well as fill you in on
- enzymes (catalysis, activation eenrgy, induced fit, structure & function)

AP Lab #13: Enzyme Activity with Perioxidase

About the enzyme catalase from the RCSB PDB Protein Data Bank

Week 11: Oct. 28 - Nov. 1 (4 days: THURS - Halloween assembly; Fri - No School; Conferences)

 UNIT # 4


Lab 1

Return Tests
Lab: Respiration at the organismal level: Human Lung Volumes & Breathing Rates (Binder pg. 217 and 219+) Lab Lung Volumes & Breathing Rates ppt

Text 7.6 and 34.6;
Watch Bozeman's the Respiratory System (9 min) and part of Homeostatic Evolution (about respiratory system evolution from min. 7:30 - 11:20)
We won't be covering the human body completely. Here is an interesting video with lots of visuals about Inside the Living body (90 min.)
Class 2

Glycolysis (pg. 207+)
Introduce Krebs cycle

Text 7.2

Optional: Bozeman's the Mitochondrion
Lab 2

Complete Data Gathering for Lab: Respiration at the organismal level: Human Lung Volumes & Breathing Rates (Binder pg. 219+)
Evaluate data for two questions (See lab) Lab Lung Volumes & Breathing Rates ppt
Adaptations for maximizing Oxygen Intake

Text 34.5 and 34.7
Finish Follow up to AP Lab #6, Rate of Cellular Respiration (explained in class);
Read: Making the most of muscle oxygen
Class 3

No School - ISACS & Parent Conferences

No School
Week 12: Nov. 4 - 8
Class 1

Krebs Cycle & Electron Transport Chain

Text 7.3 and 7.4; Start: Research and write about one food or product produced using fermentation (See Binder pg. 215);
Lab 1

Thermoregulation: Binder page 213
Lab: The Effect of Temperature on the Heart Rate of Daphnia (Homeostasis) Binder 233+-- Share Data; Construct graph, add trendline, and R2 value Lab Daphnia & Thermoregulation ppt

Watch Bozeman's Thermoregulation (5 min) and
Watch Bozeman's explanation of the Q10 calculation (3.5 min) and
Watch Undead zombie flowers of Skunk Cabbage (Plant melts snow)
Class 2

Do an accounting of all ATP ProductionBinder ??;
Calculate Percent Efficiency
Anaerobic Respiration - How to recycle the NAD+ when no oxygen is available.

Text pg. 157 and sections 7.5 & 7.6
Finish: Research and write about one food or product produced using fermentation (See Binder pg. 215);
Try the review respiration multiple choice questions beginning on Binder p. 237+

Lab 2

Lab: Absorbing Light for Photosynthesis (leaf pigment chromatography & Rf values, absorption spectrum; leaf structure ) (Binder pg. 247+);
Do Leaf Chomatography both qualitatively and quantitatively. (Use a spectrophotometer)
Different chlorophylls and pigments - give greater flexibility to exploit/absorb incoming wavelengths of light


Text 8.1 & 8.2 (through p. 173) and text pg. 597 (on leaves);
Optional but interesting: The Chemistry of Fall Colors
Class 3

Application: Adaptations of Human Respiratory systems (Binder pg. 227+) Respiratory Systems & Gas Exchange ppt
Application: Adaptations for Gas Transport in Humans - Hemoglobin (Binder 229+) Respiratory Systems & Gas Exchange ppt
Look at Adaptations of Respiratory Systems for other animals
Different types of hemoglobin maximize oxygen absorption at different devleopental stages

Review for test

Lab Report: Lung Volumes & Breathing Rates Binder pg. 219+ (details explained in class)
Week 13: Nov. 11 - 15

 UNIT #5


Class 1

Test: Unit #4 Energy Processes, Celluar Respiration & Gas Exchange & Transport; Chapters: 7, 34 (parts 34.1, 34.3, 34.5 - 34.7)

Prepare for TEST - Test Essay: See below


STUDY GUIDES Ch. 7: Focus Questions: All except 7.6 Structure your knowledge: 3 Multiple Choice: All
Ch. 34: Focus Questions: 34.10, 34.11 Structure your knowledge: 2 Multiple Choice: 20 - 26 (Respiration)

#238. - See page 32 in your binder (The question has a diagram, too hard to reproduce here).

OTHERS Objectives for Unit #4
Working with Data: Chemiosmosis, Air Flow in Birds, Measuring Residual Volume,
ESSAYS 25, 36, 63, 101, 105, 117, 127, 133,  165, 194, 6, 25, 37c, 42, 48b-c, 63, 71a,  80a, 87, 117b, 133, 141, 163, 194, 205, 17, 32, 54, 72, 80, 84, 96, 119, 130, 133, 146(e), 149, 155, 156B, 176, 200, 238

Mr. Anderson (Bozemean Science)can talk you through...
- and overview of cellular energetics in general (respiration and photosynthesis)
- how matter cycles: the hidden part of cell respiration
- The Role of Oxygen in Respiration
- LAB: Alternate Respiration Rate of Organisms technique
- The functioning of the Respiratory system
- The functioning of the Circulatory system
- The transition from water to land in respiration (second half from min 6:40 - end)
- Introduction to Thermoregulation
- Organsystems & Cooperation
- Thermoregulation
- LAB: The Q10 Coefficient

Kahn Academy will give you (more slowly)

- series of lectures on the details of respiration
- Red Blood Cells
- the Lungs & Pulmonary System
- Hemoglobin

Need a Break in Studying? Try Tom & Dericks' Respiration Song: Oxidate It or Love It

How to apply digital filter to Vernier's EKG trace (for your teacher)

Lab 1

Intro to AP Lab #5: Measuring the rate of photosynthesis in leaves: Leaf Disk Flotation (Overview - Williamson).
What is the effect of light wavelength and/or light intensity on the rate of photosynthesis? Class experiment. Share Data in Google Sheet - Do Demo

Bozeman's video The Chloroplast
Read & Bring AP Lab Manual: 61 - 68;
Watch Sinking Leaf Disks (4.5min) & Photosynthesis Lab Walk Through (6.5 min);

Class 2

Chloroplast Structure  (Binder pg. 255+
Introduce Light Reactions
Share Data from Leaf Disk Flotation

Read Text 8.2 (start pg 173)
Watch Animation on Photosnthesis: Converting light energy to chemcial energy 7.5 min - Med. Animations

Lab 2

Share data for the Quantitative Spectrophotometer readings of Spinach and one other leaf type
Lab: Measuring the rate of the light reactions using DPIP; Using a spectrophotometer to determine the effect of light's presence and boiling chloroplasts on the rate of DPIP reduction.(Binder pg. 267-270)

Watch Bozeman's Photosynthesis
(If you you didn't already.)
Read Binder pg. 267, intro to the DPIP lab.
OPTIONAL: Watch Mr. Bleier's DPIP Lab setup for DPIP experiment

Class 3 Light Reactions (Diagrams Binder 257+) Photosynthesis ppt
Begin: Photosynthesis: Dark Reactions - Making Carbon Compounds (Binder 259) Photosynthesis ppt (Pop beads can be used to follow the carbons)

Complete Chromatography & Leaf Anatomy Lab follow-up (Binder 251-253) This 2 min. Leaf Structure video and this 3.5 min. Structure of the Leaf video will be helpful for finishing the lab

Work on lab: Leaf Disk flotation (See below); Color Filter Spectra
Text 8.3 (to pg. 174)

Absent today? Here and Here are videos that explain the light reactions. Khan Academy does a nice job, too.

Lab Report on Leaf Disk Flotation:
(1) Draw a well labeled picture or set of pictures illustrating the procedure that your team did
For each of the two questions (What is the effect of (a) Light intensity and (b) Color of Light on the rate of photosynthesis in spinach?):
(2) Write a hypothesis/method/prediction statement for JUST THE COLOR OF LIGHT QUESTION. Feel free to write this in several sentences.
(3) Construct a data table and a graph FOR JUST THE COLOR OF LIGHT QUESTION; no statistics are necessary
(4) Evaluate the results with reference to your hypotheses FOR JUST THE COLOR OF LIGHT Question; (a) use data to determine if the hypotheses are supported; (b) address any unexpected results; (c) identify two things about the procedure that we did not or could not hold constant that may have affected our results
Week 14: Nov. 18 - 22
Class 1 Calvin Cycle
Text 8.3
Video: the Calvin Cycle
Questions and Graph for DPIP experiment due today.
Lab 1

Lab: Set up Sordaria Crosses

Review Light & Dark Reactions
Review: Compare Respiration & Photosnthesis (Binder p. 279-280)
Review: Multiple Choice Questions ( Binder pg. 271-275+)
Review: Leaf Anatomy (Binder p. 276)

Work on Lab Report: Leaf Disk flotation (See above assignment)

Watch Bozeman's Photosynthesis & Respiration as a good review of the molecular processes;

Binder pg. 271-280  (MC & Leaf Anatomy) (Answers will be posted here
Class 2

Application: Adaptations in Plants for Photosynthesis under hot dry condidtons: C3, C4, CAM & Others (Binder pg 261+) Short Powerpoint with Notes Here
Watch Photosynthesis Part 5: C4 and CAM
Work on some review problems

Work on Leaf Disk Flotation Lab;
Text 8.3 (start pg. 179)

OPTIONAL: Missed class today? Try this video Photosynthesis Part 5: C4 and CAM that we watched in class and another that is further explanation of how C3 and C4 plants do photosynthesis

Lab 2

AP Lab #7: Statistics: Chi-Square Analysis Use Pennies, M&Ms, & Dice (Binder 283+)
(Practice Problems Binder pg. 289-290); Table of values pg. 287)
Mitosis ppt

Lab Report on Leaf Disk Flotation Due today.
OPTIONAL: For our lab, watch Bozeman's Chi-square presentation
Class 3 Test: Unit #5 Photosynthesis & Adaptations; Chapters: 8 and pg. 556 & 565
(You will need to compare Photosynthesis to Cellular Resp.)
Prepare for TEST - Essay written during test
STUDY GUIDES Ch. 8: Focus Questions: All except 8.7 Structure your knowledge: 1 (make on another sheet of paper and insert into the study guide: DO FOR SURE!) Multiple Choice: All
OTHERS Objectives for Unit #5
ESSAYS 6, 25, 37c, 42**, 48, 63, 71,  80a, 87 (very long), 117b, 133(a), 141**, 163**, 194, 205**, 133(a), 222** The ** indicate likely question for the TEST; you will write your essay during the test.

Mr. Anderson can talk you through...
- and overview of cellular energetics in general (respiration and photosynthesis)
- LAB: How to Find Stomata
- LAB: Walk Through Floating Disk Lab
- Photosyntheis (Light Rx, Calvin Cycle, Photorespiration & Adaptations to prevent it)

-Lab Technique: Mr. Bleier's: Using DPIP to measure rate of photosynthesis

- Help with C4 and CAM metabolism: Watch Photosynthesis part 5: C4 and CAM

Kahn Academy will give you (more slowly)
- background on oxidation & reduction plus ATP
- series of lectures on the details photosynthesis. Kahn includes a discussion of Photorespiration and C4 Photosynthesis, too.
- Animation on Photosynthesis
- Crash Course: Photosynthesis
- Leaf Structure's Adaptations for photosynthesis

Only for Those who are fascinated by C4 plant evolution (technical article)

Week 15: Nov. 25 - 29 (No Wednesday, Thursday or Friday: Thanksgiving)

 UNIT #6


Class 1 Return Tests
DNA, Chromososmes, Diploid vs Haploid, Homologous Pairs of Chromosomes
Mitosis & The Cell Cycle (G1, S, G2, M) -
Do Matching Practice (Binder 301)
Text 9.1
Watch several of these videos:
Cell Cycle & Mitosis (6 min.- Med. Animations) and Mitosis Made Super Easy and BioFlix Mitosis (3 min) and Bozeman's Phases of Mitosis (12 min)
Lab 1

Introduction to Mitosis and the Cell cycle (Binder pg. 293+ and 285+); Practice Chi-Square Problem (pg. 279-80) Mitosis ppt
AP Lab #7: Mitosis Sequence; Model Mitosis with chromosome beads (Make microscope observations; determine time/phase - page 281)
Lab: Microsocpe ID of Mitotic stages (pg. 291-292)
Times for mitotic stages
Cancer - compare times

Text 9.2 especially figure 9.7:
Bring AP Bio Lab Manual;
OPTIONAL: Confused about the difference between Haploid and Diploid? Try Bozeman's Diploid and Haploid Cells

**NOT WORKING AS OF JULY 2019 ASSIGNMENT: Watch these videos in preparation for class (links on upper left side of page) The Cell Cycle, Live Animal Mitosis and Plant cell Mitosis. Watch phase contrast microscope mitosis for OPTIONAL GAME (For later in our unit): The Nobel Prize website discusses the discovery of cyclins and CDKs. There is an interactive game about cell cycle control.
Class 2

No School - Thanksgiving

No School
Lab 2

No School - Thanksgiving

No School
Class 3

No School - Thanksgiving

No School
Week 16: Dec. 2 - 6
Class 1

Meiosis (Diagrams Binder pg. 299+); Meiosis ppt
AP Lab #7: Modeling Meiosis with popsicle sticks & bead chromosomes;
Do Mitotic Division in Cancer Cells (Binder 303);

In class try chomosome Numbers (Binder pg. 309)

Lab 1

AP Lab #7: Sordaria Crossing Over Analysis (Binder pg. 321+) Sordaria ppt (Cards available);
Calculate Map distance (Binder p. 321+)
How to use Chi-Square to compare expected and observed cross-over frequencies

Bring AP Lab Manual (S93-S96)
Watch Bozeman's The Sordaria Cross which will help explain what we are doing in Lab today.

(Optional: Review Mitosis by watching BioFlix Mitosis Bozeman's Phases of Mitosis)
Class 2

Meiosis (draw); Nondisjunction
Creating Variation (4 ways)
Meiosis & gametogenesis in males & females Reproduction ppt

When is Meiosis used by animals, plants, & Fungus? Life Cycles in Animals, Plants & Fungi - Compare


Text 10.1 - 10.2, 36.1 Fig. 36.9; Watch Meiosis: Crossing Over and Variability (7 min.- Med. Animations)
Do Practice Chi-Square Problems (Binder pg. 290 #2 and 3)
Optional: Mitosis v. Meiosis (tutorial);
Radiolab (NPR Program) has a fun segment on why organisms produce so many sperm. If you have long drive (23 minutes) try listening: Why so many sperm? and on the way home (20 min) you can find out why males have persisted so long even though they seem unnecessary Deep Freeze. Another 10 minutes and you can find out about wood mice sperm who form cooperative "Sperm Trains."
Lab 2

Lab: Squash & Smear of roots exposed to Lectin & Caffeine (use cards) AND measure length of roots & compare (Binder 297+);
AP Lab Manual and (Binder pg. 297+)
Because of the timing of Thanksgiving holiday, this lab may need to switch days

Text 10.3 - 10.4 Read & Bring AP Lab Manual pg. 83 - 90
Work on Sordaria Lab Follow-up Binder 335-339.

Watch: History of HeLa Cells (9.5 minutes) or Listen to Radiolab's Henrietta's Tumor (25 min); (You will write about it soon)

Class 3

Mitosis - Control of Mitosis -- How does a cell know when it's time to divide? (Binder 319+); Checkpoints, Cyclins & CDks; Mitosis Regulation ppt

Intro to Cancer; Discuss HeLa Cells (Binder pg. 305)


Text 9.3; Watch The Cell Cycle: Cyclins and Checkpoints (1 min)
Helpful: Cell cycle Control (1 min)
Do Henrietta Lachs & HeLa Cells Research Assignment (Binder 305)
Work on Sordaria Lab Follow-up Binder 335-339

In preparation for your test, you can try these binder pages over the weekend: 301, 315, 317-318

OPTIONAL: Watch Role of RAS & p53 (2.5 min Biology Animation videos) in cancer;

OPTIONAL: Confused by cyclins & cdks? Try watching other teachers lectures Regulation of Mitosis or Regulations on the Cell cycle or Cell Division: cyclins, MPF (esp. from 1:30 - 5:50)

Week 17: Dec. 9 - 13 (English paper due friday)

 UNIT #7


Class 1

Cancer & Control of Cell Division

Intro to External Cell Signaling & Communication: Signal Transduction Pathways (Binder 343+) (Next Unit); Use Bozeman's Signal Transduction Pathways or Signal Transduction Pathway and Gene Expression (about epinephrine's action) Use epinephrine (glycogen --> glucose) as example that uses signal transduciton pathway as response to environment
Activity: Amazing Cells: Cells Communicate
Cancer & Disruptions in cell signaling

Cell Signaling ppt

Bahe's Cell Signaling & Communication ppt

Text 5.6 and Text 32.3 (Homeostasis pg. 678-680) and 32.2 pages 712-713 (Insulin & glucagon);
Do follow-up to Sordaria lab (Binder Binder 335-339)

Optional: Why bears don't get diabetes like we doText 36.3 (not pg. 774);
Optional: The Learn Genetics Website has The Inside Story of Cell Communication tutorial and Cell communicadtion involved in the Flight or Fight response.
Lab 1 Test: Unit #6; Chapters: 9, 10
Second Period: Applications of Signal Transduction Pathways & Cell Communication
Prepare for TEST
STUDY GUIDES Ch. 9: Focus Questions: All Structure your knowledge: 1, 2 (Write #2 on pg. 76) Fill in the blank: All Multiple Choice: All
Ch. 10: Focus Questions: All Structure your knowledge:1, 2 (note those that make it unique compared to Mitosis) Multiple Choice:All
OTHERS Objectives for Unit #6
Working with Data: cAMP
ESSAYS 93, 98, 134, 147(a), 53, 132, 160, 161, 169, 78, 84d, 103, 114c, 115, 146(a,b), 160B, 164C, 201, 142, 22, 80b, 100, 103, 112, 139, 169, 30, 100, 1, 18, 23, 77, 95, 115, 131, 158, 160B, 228, 240, 244 (Unit 7)

Mr. Anderson can walk you through
- mitosis, meiosis & the Cell Cycle,
- Phase of Mitosis - Events of each Phase
- Cell Division (Binary Fission, Mitosis, Meiosis)
- The Chi-Square Statistic
- what is cancer?
- LAB: The Sordaris Cross

- Cell cycle and Mitosis -> Great overview animation from Medicine Animations
- How the Cell Cycle Works --> from Medicine Animations (includes Mitosis)
- Meiosis: Crossing Over & Variability from Medicine Animations

Kahn Academy will give lectures on
- chromosomes, chromatids, and chromatin
- the phases of mitosis
- the phases of meisosis
- cancer

Animaltion: Role of p53 in cancer
All about HeLa: the Radiolab podcast and the Smithsonian interview with Rebecca Skloot, author of The Immortal Life of Henrietta Lacks.
Raven's animations: Signal Transduction,

People simulating sperm: The Great Sperm Race: Part I Part 2 Part 3 Part 4 Part 5 Part 6 Fun way to learn a little biology (Each part is about 10 minutes)

Mitosis in a Blood Lily

Class 2

APPLICATION: Hormones & Signal Transduction Pathways (Binder 361)
Hormone Action: Steroids v. Protein Hormones;
Feedback in the Endocrine system;
Apply to Glucose, Insulin & Glucogon (Diagrams Binder 361) - Emphasize Negative Feedback Loop
Use Oxytocin for Postive Feedback Loop
Endocrine System ppt (part of Signal Transduction ppt)
Insulin Signaling Pathway

Watch Bozeman Positive & Negative Feedback (start about min 8:20) and Homeostasis in the Human Body (5 min - Med. Animations)
Diabetes Type 1 and Type 2, Animation (4 min)

Lab 2 Lab: ELISA Reaction (Binder pg. 347+) Lab ELISA ppt;
Show with Lab: BioRad's ELISA Explanation
Turn in Lab results at the end of the lab - Which Panda is ovulating?
Read Background on ELISA Binder 347-349 and watch this animation (2 min) and this animation (2 min) about the ELISA procdure; they help with the reading;
Class 3 APPLICATION: Immune System: Communication within the Immune System
Immune cells interact by cell to cell contact - APCs, T-helper cells
Cytokines regulate gene expression to allow for cell replication and division
(Binder pg. 349+)
Bahe's Cell Signaling & Communication ppt
Text 35.2 and 35.3
Watch: Bozeman's Cell Communication

Optional: Cancer & Immunotherapy
RadioLab has entire episode about Blood including a timeline on the history of blood, where the hosts "consider the power and magic of the red liquid that runs through our veins." Here's a one minute news clip from AAAS Sciencenetlinks on other rare types of blood
Weekend Review Session: Saturday (12/14/19) Afternoon, time 2:30 pm, @ JBS
Week 18: Dec. 16 - 20 Exams!!!
Monday Exams: History (10 am) Prepare for your AP Bio exam
Tuesday Exam: Science (10 am) Review PPT Review sheet in binder pg. 363-373 Bring questions to discuss
Wednesday Exam: Math (10 am) Study for your other exams
Thursday Exams: Language (10 am) Study for your other exams

No School - Winter Break Begins!

Lab 1 - Period 1 Test: Unit #7; Parts of Chapters: 5, 16, 32, 33, 35, 36
Cell Signaling, Hormones & Immunity
Use for Exam
STUDY GUIDES Ch. 5.6: Focus Questions: 5.10 - 5.12 Structure your knowledge: 3 and 4 (Try to write these on the bottom space on page 47) Multiple Choice:19 - 24
Ch. 32: Focus Questions: 32.4 Structure your knowledge: None Multiple Choice: 4, 6,  9
Ch. 33: Focus Questions: 33.8 only
Ch. 35: Focus Questions: 35.2, 35.3 (c & d), 35.4, 35.5, Structure your knowledge: 1, 2 (We will probably have done something like #1 in calss together; use another sheet of paper) Multiple Choice: 7, 9, 10, 12, 16, 18
OTHERS Objectives for Unit #7 On Saturday we will have an exam review in the afternoon. Details TBA.
Working with Data: cAMP
ESSAYS NO ESSAY ON THIS TEST; JSUT MULTIPLE CHOICE 93, 98, 134, 147(a), 53, 132, 160, 161, 169, 78, 84d, 103, 114c, 115, 146(a,b), 160B, 164C, 201, 142, 22, 80b, 100, 103, 112, 139, 169, 30, 100, 1, 18, 23, 77, 95, 115, 131, 158, 160B, 228, 240, 244, 252

Mr. Anderson can walk you through
- evolution of cell communication
- cell communication
- signal transduction pathways
- effects of changes in pathways
- signal transduction & gene expression
- positive & negative feedback loops (including diabetes)
-the endocrine system
- Homeostatic Disruptions including dehydration
- The Reproductive System
- Development: timing & coordination
- The Immune System
- Vaccines & Herd Immunity
- Blood Types
- Animal and Plant Defense Mechanisms
- Review: Homeostasis (more than this unit)

LAB: ELIZA: Good Animation; Silent animation; From BioRad (our lab); From Sumanasic; From a BioRad company; The Biology Project; from U. of Michigan;
HHMI's Virtual ELISA Lab

Kahn Academy will give lectures on
- an intro to the endocrine system
- Glucose, insulin & diabetes
- cancer
Kahn has a ton of lectures on - The circulatory system including heart strucutre & function, thermoregulation in circulation, arteries v veins, blood pressure, heart depolarization

Crash Course: Your Immune System (nice review - entertaining talker)

Animation: Role of p53 in cancer
Harvard's Glucose Homeostasis tutorial
Raven's animations: Signal Transduction,

Hematology - the Coagulation Cascade
RadioLab discusses the first HIV/AIDS patient.

CBS News: Antibiotics & Food SupplyI, Part II

Winter Break: Dec 20 - Jan 5, 2020

 UNIT #8


Week 19: Jan 6 - 10 Welcome back!!!
Class 1

Pass out new Spring Binder; keep fall pages handy at home.
Experiments to Discover DNA is Hereditary Molecule (Griffith, Avery, Hershey & Chase - Binder pg. 11+) DNA ppt

Text 3.6, 13.1,
Watch: What is DNA? (10 Min. - Structure) & DNA & RNA Part 1 (12 Min. Experiments)
OPTIONAL Watch: Crash Course in DNA Structure & Replication (a little entertaining - 13 min);
Optional Watch if absent: HHMI's Summary of History of DNA Discovery (17 min)

Absent? Try this video on Avery's Experiment and this one on Hershey Chase's Experiment
More options if absent: Try this MIT DNA lecture (Griffith/Avery 1:40- 12:00; Hersey/Chase 21:00-31:00 min) & Hershey Chase Experiment Explained; Optional: More on the history of the discovery of DNA]

Lab 1 - Period 2 DNA: History of Discovery --> Watch Photo 51 (Rosalind Franklin);
Structure of DNA (Binder pg. 9+) DNA ppt

AP Lab #9: Paper Activities in preparation Genetic Engineering Experiments (Binder 15-25); Choose one application of CRISPR OPTIONS (Binder pg. 95) to reseaerch

Text 13.4**
(Absent? Watch Photo 51)

**This is an introduction to many techniques (Plasmids as vectors, gene cloning, restriction enzymnes, electrophoresis, PCR, & DNA Sequencing). Over the next 3 weeks you will be using nearly all of thse techniques and will become much more familiar with them.
Class 2

Meselson Stahl Experiment (Binder pg. 27)
DNA Replication - (Practice models available) (Binder pg.29+); Telomeres DNA ppt

Show Nucleotides asre added in DNA Replication

Text 13.2 - 13.3;
Watch Bozeman's DNA Replication (10 min) and DNA Replication (6 min) (DNA Replication process 3D Animation; also here); More on Telomeres
Optional: Watch Bozeman's Meselson & Stahl Experiment
Missed class today? Try DNA Replication from MIT (very good)
Lab 2 AP Lab #9: Restriction Analysis of DNA (Binder pg. 35+) Genetic Engineering ppt

Text 13.4** (See above)
Watch Bozeman's Molecular Biology (14.5 min);
Read & Bring AP Lab Manual pg. 111 - 115; (LATER: Extra Restriction Map Practice)

Class 3 AP Lab #9: Follow up to Restriction Analysis (Binder pg 38+) - Construct a graph to determine fragment length;
Calculating the fragment sizes on the agarose gel (lab followup - Binder 38 - 41 plus handout)
How to Make Restriction Maps (Binder pg. 107-111)
IF you don't know how to use semi-log grpah paper, then watch semi-log graph paper (4.5 min)
Watch How to make a restriction map
Week 20: Jan 13 - 17
Class 1

Transcription & The DNA Code (Binder pg. 43+);
DNA Code Practice - Binder pg. 49 & 51
RNA processisng in Eukaryotes DNA & Protein Synthesis ppt

Preview Lab on Bacterial Transformation

Text 14.1 (pg. 283, 285-289), 14.2 - 14.3;
Watch Transcription & Translation (Bozeman) and DNA Structure & Genetics (7.5 min - Med. Animations - GOOD!);
Link for the CRISPR applications assignment - Due Tues. Jan 28
Optional Watch: Translation & Transcription (Crash Course);
Missed class? Try Transcription (MIT lecture)
Lab 1 AP Lab #8: Bacterial Transformation (Binder pg. 55-59) Lab Bacterial Transformation ppt Text part 14.4 (pg. 293 - 293)
Optional: Watch: Bacterial Transformation from MIT Help session
Class 2

Read results & count colonies of Bacterial Transformation
AP Lab #8: Calculate Transformation Efficiency (Binder pg. 57-59)
Begin Translation Details

Do Practice DNA Replication (Binder 33);
Write one detailed paragraph summarizing the process of DNA replication;
For absentees: How to calculate transformation efficiency (kind of confusing)
Lab 2

Lab: Drosophila Genetics; Practice distinguishing males from females; Set up Drosophila crosses (Binder pg. 121+) Drosophila ppt
Discuss Transcription & Translation; practice with DNA Code Practice (p. 51)

Text 14.4
Do practice calculating transformation Efficiencies Binder pg. 60 (#1-3)
Watch the Amoeba Sisters How Cells Become Specialized (7 min)
Optional: Stem Cells Animations (Nucelus Medical Media - 5 min)

Class 3

Complete Protein synthesis: Translation (Binder pg. 46+); Polysomes (Binder pg. 53); Discuss protein targeting - How does a protein know where to go? Watch Translation in class(from virtual cell) or DNA Translation Animation
Regulation of Gene Expression: Operons in Prokaryotes (negative control) (Binder pg. 61+)
Phet Simulation: Gene Machine: The Lac Operon (Binder 67+)

Text 15.1
Watch How Translation Works (3 min) (Medicine animations);
Watch Bozeman's Gene Regulation and The Lac Operon
Optional: Life Science - Protein Synthesis (Translation) - Nice Animations (6 min)
Read about your chosen application for Biotechnology on CRISPR

Week 21: Jan 20 - 24 (4 days; no Monday - MLK Day; MICDS Winter basketball at JBS; dance show) (thimun departs friday)
Class 1

No School - Martin Luther King, Jr. Day

No School
Lab 1 Lab: Begin Amplification of YOUR mitocondrial DNA for sequencing - Extract the DNA and set up PCR (Carolina Biological - Binder pg. 77-86);
PCR Process (3 min)
PCR Simulation to predict disease in patients
Read & Bring AP Lab Manual pg. 97 -102;
Watch PCR Animation (very good, but slow - 5 min);

Read about your chosen application for Biotechnology on CRISPR
Class 2 Continue Regulation of Gene Expression: Operons in Prokaryotes (negative control) (Binder pg. 61+) Phet Simulation: Gene Machine: The Lac Operon (Binder 67+)
Model Operon control with playdoh
Discuss Types of Mutations (Point, Frameshift, Chromosomal Mutations, Trinucleotide repeats - Binder pg. 87);
Text 15.1, 14.5
Bring AP Lab Manual;
Read Binder pg. 77-79 (More background to lab); Watch Bozeman's Mutations; Optional: Example mutations with human diseases
Lab 2

Lab: Set up Electrophoresis of your DNA sample; Run (Binder 77+)

Do Genetic Testing Exercise (Binder 97-103)

Regulation of Gene Expression in Eukaryotes (Bnder 73) Eukarytoic Gene Regulation ppt;

If ready, do practice for DNA and BioTech (Binder p. 117 #1, 2, 3, 4, 5, 6 (try), 7, 8 (very challenging - putting lots of stuff together), 9)
After Class if you are still confused try: Regulation of Gene Expression: Operons, Epigenetics, and Transcription Factors

Text 15.2 & Review Text 13.4;
Watch Regulated Transcription
Optional: Very nice animation review of transcription & translation McGraw Hill

Class 3 Lab: Read your electrophoresis gel of your DNA sample; Bahe will send for sequencing
Complete Gene Expression in Eukaryotes
Cancer - Lack of control --> Genes gone haywire; (Binder pg. 89+
Viral Reproduction - Using Viruses as Vectors for Biotech (Binder pg. 89+);
Text 17.2; Watch Bozeman's Viruses and Viral Reproduction
Optional: FYI Viral Evolution
Week 22: Jan 27 - Jan 31 (THIMUN returns)
Class 1 Follow-up Biotechnology: How to find a gene; Putting together the Biotechnology tecniques (Binder 91-94, 111-115)
Review of BioTech ppt
Text 13.4, p. 353
Lab 1

Lab Round Robin Presentations: The Applications of CRISPR (Biotechnology);

Review for test; discuss essay on biotechnology

Make your slide presentation in our Google Presentation about one application of Biotechnology CRISPR.
Link for the original CRISPR applications assignment
Optional: NPR's Radiolab podcast on CRISPR's update (second half is the update; entertaining)
Optional: Science's annotated paper on CRISPR
Class 2

Test: Unit #8; Chapters: 3.6, 13, 14, 15.1, 15.2,17.2

Prepare for TEST
STUDY GUIDES Ch. 13: Focus Questions: All Structure your knowledge:1 and 2 (Write on a sheet of paper) Multiple Choice: All
Ch. 14: Focus Questions: All Structure your knowledge: 2, 3 (Write #3 on the bottom of page 115) Multiple Choice: All
Ch. 15.2: Focus Questions: 15.1, 15.2, (15.4 labels here are notimportant; do you udnerstand this diagram?) Structure your knowledge: 1, 2 (a, b, c) Multiple Choice: 1, 2, 3, 4, 5, 7, 8, 9, 11, 12
OTHERS Objectives for Unit #8
Working with Data: Determining Paternity, The Genetic Code, Recombinant DNA, Genomes, Cloning,
ESSAYS 37a, 76, 88, 114d, 144, 24, 35, 47, 64, 94, 106, 120b, 121, 144,  147(b), 152, 168C, 170, 183, 196, 206 (a, b), 9, 15, 16, 82, 134, 147(c), 156A, 160A, 164A, 166, 160A, 196 (c), 15, 88, 120, 128, 138, 153, 180, 196, 197, 207, 225, 233, 236 (b)(Ch 21: 15, 88, 120, 128, 138, 153, 180), 248, 250

Mr. Anderson will explain
- Nucleic Acids and What is DNA?
- DNA & RNA Part I (History of the discovery; Pro- v Eukaryotic Chromosomes)
- DNA & RNA Part II (Replication & Protein Synthesis) and DNA Replication (includes Meselson-Stahl Experiment) and Meselson Stahl Experiment Itself
- Transcription & Translation
- Gene regulation in Prokaryotes & Eukaryotes
- The LAC Operon
- Viral Replication
- Epigenetics
- Techniques of Biotechnology
- Signal transduction & gene expression
- Molecular Biology (Nice intro/summary of genetic engineering)

DNA Replication from Medicine Animations - GOOD!
Restriction Enzymes from Medicine Animations
How Translation Works from Medicine Animations

Epigenetics (See Bozeman, too):
Ghost in your genes (Nova's program on epigenetics)
Ghost in your genes (BBC's pgogram on epigenetics)

Phet Simulation: The Gene Machine: Lac Operon

Kahn Academy lectures about
- DNA (sections on Dentral Dogma, replcation, the geentic code, protein translation, and post translational modifications)
- DNA Structure & Replication (Crash Course): GOOD!
- DNA Structure & Classic Experiments - lecture segment from MIT and Part 2
- DNA Replication - lecture segment from MIT - very good
- Transcription & Translation (Crash Course): Entertaining, too.
- Transcription & Translation (Great drawing coincides with the explanation)
- Transcription & Translation - lecture segments from MIT - Very Good
- Gene control (sections on Lac-operon, chromatin regulation, regulation of transcription, non-coding RNA and Oncogenes)
- Genetic Mutations (types, causes, carcinogens)
- An Intro to Viruses
- Restriction Enzymes (10 minutes) - Slow but clear.
- How to Map a Restriction Map (a typical AP problem)
- BioRad's Restriction Digest Instructions
-From NPR: How Viruses Work (entertaining, too)-
From NDSU Virtual Cell Animations: Translation
-The Best PCR animation (it's just a little slow); clip on PCR shown in class
- From DNA Learning Center: PCR another: PCR animation
- Our Bacterial Transformation Lab
- Bacterial Transformation from MIT Help Session
- Historical 1971 reenactment of protein synthesis at Stanford. A Classic.

 UNIT #9


Lab 2


Introduction to Mendelian Genetics Genetics ppt
Video Clip: Gregor Mendel
LAB: Release Drosophila F1 flies
LAB: Corn Genetics - Monohybrid Cross
Pedigrees for Mendelian characteristics
LAB: Corn Genetics - Dihybrid Cross
LAB: Chi-Square analysis of corn data (Binder (table) 131+)


Text 11.1 - 11.2;

Class 3

Dihybrid Cross
Exceptions to Mendelian Genetics:
Multiple Alleles; Co-Dominance; Incomplete dominance; Epistasis; Polygentic Traits; Mitocondrial Inheritance; Influence of the environment

Text 11.1-11.2
Mendelian Genetics Problems (Pg 147 #5, 6, 7 Pg. 148 #1, 3, 4, TEXTBOOK pg. 234 #3, 4, 13)
Check our website daily for the problems assigned in class. Please always do genetics problems on separate sheets of paper.
Week 23: Feb. 3 - 7 (No Friday - Professional Day)
Class 1

Continue with Some Exceptions to Mendelian Genetics:
Multiple Alleles; Co-Dominance; Incomplete dominance; Epistasis; Polygentic Traits; Mitochondrial Inheritance; Influence of the environment

Text 11.3;
Write essay on BioTechnology (Handed out in class)

Lab 1
Lab: DNA Extraction from Berries & Other Organisms (Binder pg. 133)
Lab: Predigrees (Binder 147+)
Practice Problems on More Exceptions to Mendel

Do Genetics Problems: Pg. 149-150 (#3, 4, 5, 8, 10, 11, 12)

Binder Pg. 141 (all - it's one problem), p. 151 (#2, 3, (you might need a 4x4 square here)) - (Note Text pg. 224 is useful for more explanation of today's class on Dom,Incomplete Dom, & Co-Dom)

Class 2 Pleiotropy, Newborn Screening
Environment (examples: height & weight, hydrangea, seasonal fur color, sex determination in reptiles, UV on melanin production, yeast mating types)
Practice Genetics Problems - Exceptions to Mendel;
Introduce Sex-Linkage;
Test your Color vision here. or here.
Sex determination in other organisms (Birds - ZW; Bees - Haploid/Diploid)

Text 12.1- 12.2
Do Genetics Problems: Pg. 153 (#1, 3, 4, 5, 6 - you must use two pairs of genes for #6) and page 151 #6 and 7

Absent: Try this video on Sex Linked Inheritance

Lab 2

Lab: First count the F2 Drosophila Flies (Binder pg. 125+)
Practice Sex-linkage problems (Binder pg. 142);
Sexual Development & SRY gene; Barr Bodies; Alterations in Chromosome Numbers (non-disjunction)
SRY gene gene triggers the male sexual developmnet pathway (response to envrionment)
Practice Pedigrees with human traits

Do Genetics Problems: Pg. 153 (#1, 3, 4, 5, 6 - you must use two pairs of genes for #6)
Optional: Bozeman's Advanced Genetics from 7:45-10:30 will help with sex Linkage.

Class 3

No School - Professional Day

No School
Week 24: feb. 10 - 14
Class 1 Sex-Linkage
Practice Sex-linkage problems
X-Inactivation & Barr Bodies

Introduce Autosomal Linkage (Binder p. 155) Linkage & Recombination Frequencies

Text 12.3;
Watch Bozeman's Genetic Recombination and Gene Mapping
OPTIONAL: Genetics Problems: Binder pg. 151-152 (answers on pg. 153) You should be able to do the following numbers: 1-11, 13, 14, 16-20
OPTIONAL: Watch Bozeman's Chromosomal Genetics as Review & Intro to Linkage

Lab 1

Begin with short QUIZ
2020: Due to Poetry Day, Count Flies today

Receive class Drosophila data & directions to perform the data analysis (Binder p. 127-128 ) Time to discuss crosses s

LAB: Discovering Epigenetics: "Ghost in your Genes "; BBC Version; "Epigenetics Activities" from Learn Genetics Utah (Binder pg 81+)
(Check out What is Epigenetics? with Nessey Carey)
Genetics Review (Binder pg. 151-152) Genetics ppt


Do Genetics Problems: Pg. 153 (#1, 3, 4, 5, 6 - you must use two pairs of genes for #6)
Short Quiz today
Practice Genetics Problems: Textbook pg. 234 #2, 5 (think! - no Punnett Square needed), 6a, 6c, 7, 8, 9, 13, 14 (similar to #9), 15, 18 and Text pg. 256 #2, 5) Check some answers in the back of the book.
Work on the study guide problems for chapters 11 and 12. Lots of good practice here!

LATER: Watch Bozeman Epigenetics (9.5 min);
Data Here (Will be updated)

Class 2

Discuss the Lab Report
Barr Bodies, Calico Cats & Nondisjunction
Y-Chromosome & the SRY Gene

Introduce Autosomal Linkage (Binder p. 155) Linkage & Recombination Frequencies

Discuss a Final Few Genetics Concepts (Lethal alleles)
Practice Pedigrees & Autosomal Linkage;

Begin Working on Drosophila Data Analysis as a team; check one another's work


Text 12.4;
Practice Problems Binder Pg. 145 (# Any not done in class) and Pg. 152 (#21 - 22)
Optional Text Problems: pg. 256 (#3, 4, 6, 7, 8, 10)
Work on the study guide problems for chapters 11 and 12. Lots of good practice here!
Each lab team works together to complete all 5 Drosophila analyses (p. 139-140) - Due Thursday Feb. 20th; Data Here
Optional Article: Curious chemistry Guides Hydrangea Colors (Short)

Lab 2

Complete Autosomal Linkage
Go over practice Problems

Lab: Work on Drosophila Data Analysis as a team; check one another's work

Discussion on Types of Genetic Screening
Genetic Screening - Evaluate Bioethical Scenarios

Work on your crosses of the Drosophila Lab
Practice Problems Binder Pg. 157 (# Any not done in class) and Pg. 164 (#21 - 22)
Text Problems: pg. 256 (#3, 4, 6, 7, 8, 10)
Work on the study guide problems for chapters 11 and 12. Lots of good practice here!

Class 3 Lethal Alleles
Practice Problems on pg. 158

Review for test

Drosophila Lab Report due TODAY.
Handout with answers on Genetics Problems from AP Website (#TBA)
Text 19.1

Optional: Practice Problems (Binder pg. 163-164 - Answers on pg. 165:
OPTIONAL: I recommend the study guide for the genetics unit; lots of good practice genetics problems.
Week 25: Feb 17 - 21 (4 days; No Monday - President's Day) (Fri - Grandparent's morninG, per 1-2)
Class 1

No School - President's Day

No School
Complete as much as possible on your cross of the Drosophila Data Analysis report. Bring to class to share with lab partners for editing.
Lab 2 Test: Unit #9 (double period) - time given for working out problems; Chapters: 11, 12 Prepare for TEST
STUDY GUIDES Ch. 11: Focus Questions: All Structure your knowledge: 1, 2, 3 (May need a piece of paper) Genetics Problems 1-10 (DO THESE ON A PIECE OF PAPER) Multiple Choice: All except 7
Ch. 12: Focus Questions: All Structure your knowledge: 1, 2 Genetics Problems 1-5 (DO THESE ON A PIECE OF PAPER) Multiple Choice:All
The pracctice problems in chapter 11 and 12 of the study guide are very good for becoming familiar with and testing your understanding of genetics problems.
OTHERS Objectives Unit #9;
ESSAYS 69, 98, 120a, 136, 157, 4, 15, 34, 40, 112, 120a-b, 132, 166, 203 (a, b), 219 (c), 251

Mr. Anderson of Bozeman Science will help you with
- Mendelian Geneics
- Genotypes, Phenotypes & Mutatiaons
- Gentoytpe Expression & The Environment
- Advanced (non-Mendelian) Genetics
- The Chi-Square Statistic
- Probability & Genetics
- Chromosomal Genetics & Genetic Recomgination and Gene Mapping & Linked Genes
- X-Inactivation

Kahn Academy can lecture you about
- An Intro to Heredity
- Using Punnett Squares
- Sex-linked Traits

Entertaining 10 minutes on Gregor Mendel from SciShow
Mendel - From the Garden to the Genome (Biography - 30 minutes)
About Fainting Goats & the Science behind them; watch them at Fainting Goats & at A Herd of Fainting Goats

 UNIT #10


Class 2 History before Darwin Evolution & Natural Selection ppt - What did each contribute? (Binder p. 171)

Complete as much as possible on your crosses of the Drosophila Data Analysis report. Bring to class to share with lab partners for editing.
Text 19.1
Watch: History of Evolutionary Thought (10 min)

Optional: Evolution Gems from Nature;
BBC's How Do We Know Evolution is Real? Science with Tom - Rap Song on Evolution: 3.5* 'Til Infinity

Darwin Day, Feb 12: Baba Brinkman raps an ode to Darwin. He has an entire album of rap songs for Evolution. Click HERE.
Lab 2 Lab: Bird Beak & Seed Size Simulation: The Law of Natural Selection (Binder pg. 173-174);
Optional: Use Chi-square to analyze data Evolution & Natural Selection ppt

Text 19.2
Watch Bozeman's Examples of Natural Selection

Optional: Darwin, the Story behind the Science and Wallace, the Story behind the Science Optional: Ironing it Out (Survival of the Sickest)

Class 3 Evidence for Evolution Evidence for Evolution ppt (pg. 175)
Which is most convincing?

Drosophila Lab Report due TODAY.

Text 19.3 OR Watch Bozeman's Evidence of Evolution and Evidence for Evolution II;

Absent? Watch segments of "Evidence of Evolution Made Easy"
list of resources for evidence of evolution

Week 26: Feb. 24 - 28 (Winter musical - Thur, Fri, Sat)
Class 2 Discuss causes for evolution; Practice Worksheet (Binder p. 177-178)
Three Types of Natural Selection & Maintenance of Variation (If Time, stats practice: A Case of Sexual Selection and Evolution (Binder pg. 189+))
Cornell's Ornithology Activity on Sexual Selection and the video resources

Text 21.3, 21.4

OPTIONAL: Do Online Activity: Visualizing Life on Earth: Interpreting Data;
Lab 1

Lab: Hardy-Weinberg Simulation (cards) (Binder pg. 179+);

The Assumptions for Hardy-Weinberg and Change in Gene Frequencies -> Microevolution;
Use Evaluation Causes of Evolution (Binder 205+ - select #)

Bozeman's The Five Fingers of Evolution


Text 21.1-21.2;
Do Practice Evidence of Evolution (Binder pg. 177-178)
Watch Bozeman's Genetic Drift
Read: Evidence for current evolution: Chlorea and Bangladesh
Class 2

Practice of Hardy-Weinberg problems

Do HW Problems Binder pg. 188 (#1 - 6)
There are many more practice problems on pg. 211+ which we will do later.
Lab 2 AP Lab #2: Computer Modeling Hardy-Weinberg: Set up the model using Excel; Select a Question to answer with your model (Binder pg. 197+)
Lab: Using AlleleA1 for Mathematical Modeling of H-W (Binder pg. 201+) More simulations: U. of Wash.and Radford U.;
Do H-W practice problems p. 211-213) #1, 3, 6, 9 (harder), 11, 13 (hint, determine p & q in current population and then use these to predict the next the generation; are they the same?), 17 (remember the rules of probability), 25
Read & Bring AP Lab Manual pg. 25 - 29;
Helpful for absentees: Hardy Weinberg Equation and Five Fingers of Evolution (5 min)
Class 3 What is a species?
Speciation: Allopatric & Sympatric Speciation ppt;
Reproductive Isolation & the Tempo of Evolution
(Binder pg. 215 - Practice classifying Reproductive Isolating Mechanisms)
Speciation exampples: Hawaiian Drosophila, Caribbean Anolis, Apple Maggot Rhagoletis
Show short Film on Grant's work on Galopogos Islands The Beak of the Finch or on YouTube

Text 22.1, 22.2;
Read "Speciation in Real Time"
Watch Bozeman's Speciation

Absent today?
Try this lecture Speciation

Week 27: Mar. 2 - 7 (4 days - Wed. MAY PROJECT contact & Prefect day off )
Class 1 Discuss Sympatric Speciation and Rates of Evolution.
Use evolution of the stickleback (case study) as mechanism for punctuated equilibrium (Binder pg. 217-226). Films: Bozeman's Stickleback Evolution and Evolving Switches, Evolving Bodies;The Broad Patterns of Evolution: Extinction (Plate Techtonics; Mass extinctions; Adaptive Radiations)
Text 22.4, Figure 23.22 on text pg. 476
Text 23.2, 23.4
Optional: current examples of speciation: Lizards, Mice, Palm trees, Fish; Bizarre new lizard genetics, watching speciation occur, Birdfeeders & Black capped Warblers, London's Subway Mosquito, Giant Insect Splits Cavefish
Lab 1

Using HHMI's Finches Beak to evaluate Grant's work (Binder 227-236)
Short Film on Grant's work on Galopogos Islands The Beak of the Finch or on YouTube; Sorting Finches; Excel File of Grant's Data for Statistical Data to analyze

Read these two articles about sequencing the CoVID-19 geneome:
The Scientist and L.A. Times

Class 2

No AP Bio Class; Visit your May Project Sponsor

No AP Bio Class
Follow-up to Beak of the Finch (Binder 227-226 including your 4 bar and 2 line graphs)
Lab 2

HHMI: Creating Phylogenetic Trees from DNA Sequences (Tutorial)
Sorting shells (Binder pg. 215-225) (Practice making cladograms Binder pg. 237+)

AP Lab #3: Using CLUSTALX & nPLOT (similar to BLAST) to investigate evolutionary relationships -- Ask your own Questions (Binder pg. )

Blast Education resources; practice files from AP Central

Watch Bozeman's Phylogenetics and Cladograms

Read & Bring AP Lab Manual pg. 41 - 44; Do Practice for Evolution (Binder pg. 261 - 296 #5-7, 9-13, 16-20 and write #27);

Class 3 Practice making cladograms & reading cladograms (Binder p.253+)
The Origin of Life; (Binder pg. 257,-259) Explore the timeline
The Origin of Eukaryotes (Endosymbiosis and Infolding) & Multicellularity Origin of Life ppt
Text 24.1
Complete Follow-up to Beak of the Finch (Binder 227-236 including your 4 bar and 2 line graphs - See your class for complete directions; answer all questions) Video on the Finches may help with questions (15 min)
Watch Bozeman's Endosymbiosis Optional: Origin of Multicellularity; Endosymbiosis
Week 28: Mar. 9 - 13 (No Friday - spring Break; Wed is Science test day)
Class 1

Complete Origin of Life
Evolution Review; the three Domains of Life The 3 Domains ppt

Text 25.1, 25.2
Do these multiple choice Questions: Binder pg. 261-296 # 1-4, 8, 14, 21, 35-39 and the written question on Binder 270 - Write on separate page.

Watch Bozeman's The Three Domains of Life and Three Domains of Life (Med Animations)
OPTIONAL: Bozeman has a couple of nice evolution review videos: Natural Selection Review and Speciation Review

Lab 1

Continue Evolutionary relationships using BLAST;
Analyze your own DNA - compare to classmates and worldwide
Finish using CLUSTLX, NJPLOT, & BLAST to investigate evolutionary relationships
Practice reading models and diagrams: (Parts 1 and 2)

Practice reading and making cladograms

Text 24.1, 24.4 (not pg. 472-3);
Watch Bozeman's The Origin of Life - Scientific Evidence
Do Evolution Practice (Binder 261-296+ #15, 22-26, 32-34, 40-47 and write #30)
Optional: Miller - The Story Behind the Science and ClearStated's Video of Miller Experiment
Of Possible Interest: BBC's Program, Episode 3 of the History of Science. How Did We Get Here? (52 min.) (Not working July 2019) This is the story of how scientists came to explain the beauty and diversity of life on earth, and reveal how its evolution is connected to the long and violent history of our planet. and Nick Barton's 14 min talk at the Falling Walls Conference on "Breaking the Wall that Limits Evolution: How Sexual Recombination Accelerates Adaptation." (2011)
Class 2 Test: Unit #10; Chapters: 19, 20(.1 & .3), 21, 22, 23 (23.2; 23.4) , 24 (24.1, 24.4), 25 (25.1 - 25.2) Prepare for TEST
STUDY GUIDES Ch. 19: Focus Questions: 19.1 - 19.4 Structure your knowledge: 1 Multiple Choice:All
Ch. 20: Focus Questions: 20.1, 20.3 Structure your knowledge: None Multiple Choice:1 - 6, 9 - 14, 16
Ch. 21: Focus Questions: 21.2, 21.3, 21.4, 21.5, 21.6 Structure your knowledge: 2 (Write on the bottom of page 159) Multiple Choice: All
Ch. 22:
Focus Questions: 22.1, 22.2, 22.4, 22.6 Structure your knowledge: 2, 3 (Write on the bottom of page 164) Multiple Choice: All except 2, 7, 12
Ch. 23: Focus Questions: 23.3 Structure your knowledge: None Multiple Choice: 3, 5, 7 11
Ch. 24: Focus Questions: None Structure your knowledge: 1 (Write on the bottom of page 177) Multiple Choice: 1 - 4
Ch. 25: Focus Questions: 25.1 Structure your knowledge: None Multiple Choice: None
OTHERS Objectives for Unit #10
Working with Data: Animal Phylogeny, Phylogenetics, Reproductive Isolation, Prebiotic Molecules,
ESSAYS 37b, 51, 116, 150, 160, 162, 5, 38, 67, 79, 102, 116, 121, 136, 160D, 162, 191, 195, 203 (c), 206 (c), 14, 21, 62, 91, 150, 192, 195, 143, 164A, 164D, 207 (a), 223, 230, 232, 236, 239, 243, 245 (long)

Mr. Anderson will walk you through
- Natural Selection
- Examples of Natural selection
- Cellular Variation (Examples, Heterozygous Advantage, Gene Duplication)
- Population Variation (Examples at the population level, calculate allele frequencies (HW))
- Intro to Hardy Weinberg & Population Genetics
- Solving Hardy Weinberg Problems
- Genetic Drift
- Evidence for Evolution
- Mechanisms to increase variation (in bacteria and eukaryotes)
- Populations Continue to Evolution (Types of selection)
- Speciation & Extinction
- Speciation; and Reproductive Isolation
- Stickleback Evolution
- Phylogenetics (Cladograms)
- LAB: Comparing DNA Sequences
- Abiogenesis & Miller's Experiment
- Origin of Life - Scientific Evidence
- The Essential Characteristics of Life are Conserved & Evolution of Eukaryotes
- Endosymbiosis
- The Three Domains of Life (start at 3 min - end)

The Kahn Academy can lecture you on
- Allele frequency, the Hardy Weinberg Equation, and Applying the equation

Cleearly Stated'sWhat is evolution?, Evidence of Evolution and Chemical Evolution and Can Evolution Explain the Origin of Life?
Learn Genetics: Variation + Selection & Time; Evolution in Action
PHET Simulation: Natural Selection
PBS: Why Does Evolution Matter Now

Harvard's Horizontal Gene Transfer; Molecular Evolution and The Early Earth; Speciation in Gators

Allele A1Simulation:
-Allele A1 Program Download
-YouTube Allele A1 Demo (Duke U.)

The Species Problem - Various ways to define species
Speciation by Cornell's Ornithology Lab

Lab 2

AP Lab #12: Rolly Polly behavior: Taxis (Complete in this period)
(Alternate apparatus for Fruit Fly behavior - for teachers)

Text 39.3
Read and Bring AP Lab Manual pg. 145 - 150
Optional: Ladybird Terrorists
Class 3

No Class - Spring Break Begins!!!

No School - SPRING BREAK!!

Spring Break: March 13 - 29, 2020

 UNIT #11


Week 29: March 30 - April 3 Welcome back!! (Saturday is prom)
Class 1

The Nervous System: The Neuron: Anatomy, Resting Potential, Action Potential & the Synapse (Binder pg. 281+) The Neuron ppt
Practice Labeling an Action Potential (Binder p. 285)
Neurotransmitters - Cell to cell communication

Text 37.1, 37.2, 37.3
Watch Bozeman's Nervous System; Watch Chemical synapse (1 min); Watch Bozeman's the Neuron, Resting Potential and Nerve Impulse Mechanism (4 min - Med. Animations) OPTIONAL: Bozeman's The Electrochemical Gradient
Optional: Bozeman's The Synapse & The Action Potential
Lab 1

Lab: Muscle Contraction & Fatigue (Binder pg. 319-322) Muscle Contraction ppt
Share data with a Google Sheet
The class will decide what variables to test and evaluate. You will make two graphs, one bar and one line, to look for trends in the data. You will share your graphs with the class. Due Monday April 6th

Text 31.1 (640 - 641) and/or Watch Pearson's Animation of (1) The neuromuscular junction, (2) the Excitation of the Muscle Fiber and (3) The Cross Bridge Cycle (Total time about 10 min.)
Do The Action Potential Binder pg. 285 (if we have discussed);
Read: Making the most of muscle oxygen

Class 1 Communicating between Neurons and Muscles (Synapse)
Muscle Contraction at Cellular Level (Binder pg. 311+)
Choose the questions to evaluate from the muslce data.
Text 37.4 (pg. 793-4 only), 39.1 ;
Watch Bozeman's the Muscular System: use Binder pg. 309 with this 6 min video and watch Muscle Contraction Process (4.5 min.-Med. Animations)
Lab 2 Lab: Plant Responses: Dandilion Demo of phototropism (Need Handout) if Dandilions are available;
Discuss Phototropisms & Photoperiodism (Binder 325+) Plant Responses ppt

Text 31.1 (pg. 650-2 only), 31.3;
Watch Bozeman's Behavior & Natural Selection (9 min);
Watch McGraw-Hill's animation of Phytochromes (2 min);
OPTIONAL: Watch Bozeman's Plant control (hormones)

Class 3 Plant Response: Phototropisms & Photoperiodism (Binder pg. 325+) Plant Responses ppt
Work on Data Analysis for Muscle Contraction Lab
Text 31.2
Use Binder pg. 323 as you watch Bozeman's Mechanisms of Timing (10 min);
Week 30: apr. 6 - 10
Class 1

Animal Behavior Topics Behavior & Abiotic Factors ppt
Interactions: Binder p. 333

Quorum sensing in Bacteria - Cell communication using local regulators; infomration transmitted by signal transduction pathway

Text 39.3-39.4; Watch Bozeman's Animal Behavior
Work some on your muscle lab graphs report
Optional: Animal Mind control by Parasites
; Nice; Listening to Bacteria
Work some on your lab report
Lab 1

LAB: Analyze Behavior Case Study(Kin selection of Belding's Squirrel - Binder pg.335+); More Animal Behavior videos

Make one bar graph (with error bars) and one line graph (with regression line and R2 value) from muscle contraction/fatigue data.
Text 39.6
Class 1 Population Growth & Regulation Populations ppt Text 40.3 and 40.4
Watch Bozeman's r and K Selection
Lab 2 LAB: Simpson's Diversity Index

Choose one Biome and one human intrusion for application of concepts presentation;
LAB: Begin to construct Biome Presentations (Google Doc/Triples) - Binder pg. 345

Text 41.2, 41.4, 41.5
Overview of Ecological Interactions Bozeman's Biotic and Abiotic Factors

OPTIONAL (but useful for absentees): Bozeman's Exponential Growth and Logistic Growth and Population Ecology (7 min. - Med. Animations) Mr. Knuffke's Prezi on Population Growth Review: Mr. Kuffke's Prezi on Behavior

Class 3 Population Growth & Regulation (Possible extension: Habital Planet: Interactive Labs: Disease Lab (a simulation)) (Binder pg. 349+) Populations pptEquations of Population Growth; Life Histories; Human Population Growth (Binder pg. 353 (intro problems), 355 and 357+ (many problems)) Populations ppt Text 40.5 and 40.6
Watch Bozeman's r and K Selection
Work some on your biome sllides
Week 31: apr. 13 - 17 (3 days: Wed - Health Day & Fri - Skip Day)
Class 1 Energy flow in ecosystems: Food chains & Webs (Binder pg. 367-369); Ecosystem Processes ppt Text 41.2, 42.1, 42.2
Do Intro to Population Problems (Binder pg. 353 #1, 2, 5, 6, 7, 10 (part b is asking for the net change in the population size) Answers will be posted HERE
Do Applying Concepts to Cactus Finch (Binder 355-356) Answers will be HERE;

Optional: Mr. Knuffke's Prezi on Ecosystem Structure
Lab 1 AP Lab #10: Energy Dynamics & Primary Productivity - Design an Experiment (Binder Pg. 371-374) Lab Primary Productivity ppt Text 42.3
Try Population Growth Practice Problems (Binder 357+ #4, 5, 9) Answers will be posted here;
Make 2 slides/person for your biome presentation
Class 2 No Classes: Senior Health Day No Classes Today - Work on your Biome Presentation
Lab 2 AP Lab #10: Energy Dynamics & Primary Productivity (follow-up); Measure D.O. Lab Primary Productivity ppt
(Possible extension: Habital Planet: Interactive Labs: Disease Lab (a simulation))
Watch Bozeman's Ecosystems;
Make 2 slides/person of your Biome presentation;
Try Population Growth Practice Problems (Binder 357+ #6, 7, 9, 10, next are m.c. 11, 12, 13, 14, 15, 16, 17, 18-21 graph changes) Answers will be posted here
Class 3

No School for Seniors: Senior Skip Day

No School
Week 32: Apr 20 - 24 (potpourri Week)
Class 1 Evaluate Data from AP Lab Energy Dynamics (Binder pg. 377)
Energy Flow, Food Chains, & Food Webs
Do Practice Energy flow Problems (Binder p. 379)
Communities & Succession ppt
Make 4 slides per partner of your Biome presentiation.
Optional: Mr. Knuffke's Prezi on Community Interactions
Lab 1 Videos: Community Structure: (Binder pg. 381-382)
Complete Succession and discuss Interelationship Examples Communities & Succession ppt
Text 41.1
Complete lab report on primary productivity (Binder pg. 371-374) - explained in class;

Watch Bozeman's Populations (on Population interactions) and Niche and Aposematic Coloration
Make 2 slides per partner of your Biome presentation.
Optional: Interesting story of Jerry Coyne, who has a botfly egg deposited on his head, on NPR's Radiolab (16 min).
Class 2

Finish Ecology Concepts
Ecosystem Processes ppt

Text 41.3
Watch Bozeman's Ecological Succession;
Finish polishing your Biome Presentation;
Deadly Algae in Water Supply 2014
Lab 2 Lab: Group Presentations: Biomes & Human Intrusions in Ecosystems
Review for test
Finish your Biome Presentation;
Optional: Global Warming - the Story Behind the Science and Mr. Knuffke's Prezi on Human Impacts and Prezi on Conservation Biology Another Human Intrusion: Drugging the Environment
Class 3 TEST: Unit #11; Chapters: 39.3-39.6, 40, 41, 42, 43 Prepare for TEST:
STUDY GUIDES Response & Behavior
Focus Questions: 31.3, 31.5, 31.6, Structure your knowledge: 2 (Draw this on the bottom of page 230) Multiple Choice: 7. 8, 12
Ch. 37:
Focus Questions: All, Structure your knowledge: 1 (Write a description on the bottom of pg. 286) Multiple Choice: 1, 3, 4, 5, 7, 8, 10, 11, 12, 15

Ch. 39: Focus Questions:39.1, 39.5, 39.6, 39.8 Structure your knowledge:1, 3 (Write on the bottom of pg. 304) Multiple Choice: 1, 3, 4, 5, 11, 12, 13, 14, 17, 18, 19,
Ch. 40:
Focus Questions: 40.5 - 40.9 Structure your knowledge: 2 Matching: None Multiple Choice: All except 2, 3, 5, 7, 9, 10, 11, 21,
Ch. 41: Focus Questions: 41.1, 41.2, 41.3, 41.4 Structure your knowledge: 1, 2 (Writ eon pg. 328) Multiple Choice: All except 8, 14, 15
Ch. 42: Focus Questions: 42.2, 42.3, 42.5, Structure your knowledge: 1 and 2 (Write on hte bottom of page 328) Multiple Choice: 1 - 8
Ch. 43: Focus Questions: 43.1, 43.5, 43.7 Structure your knowledge: 4 (Write on a piece of paper) Multiple Choice: 1, 2 4, 6, 8, 12, 13, 14, 15
OTHERS Objectives for Test #11 Objectives for Unit #12
Working with Data: Nickel and plants; nicotine and plant defense; Eyes and Rods;
Working with Data: Habitat Fragmentation, Wildlife Corridors,

Response & Behavior: 23, 59, 146(d,e), 149, 158, 7, 8, 44, 60, 114b, 115, 130, 149, 164C, 178, 8, 44, 84c, 89, 122, 149, 155, 177, 8, 44, 84c, 89, 122, 149, 155, 177, 234, 241

Ecology: 1, 18, 23, 77, 95, 115, 131, 158, 160B, 208 (b), 168A, 179, 181, 186, 189, 208, 20, 26, 50a, 61a, 104 cd, 134, 159, 168A, 174, 10, 33, 50b-c, 61b-c, 104a, 148(a), 164, 204, 12, 45, 46, 76c, 73, 85, 92, 104b, 110, 118, 140, 151, 160C, 164B, 172, 184, 194, 221, 224, 231, 237, 242, 245 (long), 246 (long) , 247, 249, Review Essays 187, 190


Mr. Anderson can walak you through
- Nervous System
- The Sensory System
- Muscle System
- Behavior & Natural Selection: Plant Response, Pollination, & Animal Mating Strategies
Mechanisms of Timing- Phototropism, Photoperiodism, Circadiam Rhythms, & Quarum sensing in bacteria

- Resting Potential by Pacific Media and Action Potential by Medicine Animations

- Why do your knuckels crack (explanation) and video?

History: Recording an Action Poential by Hodgkin; Squid Axon Nerve Removal (MIT)
Kahn Academy can lecture you about
- The Nervous System (neurons, the Na+/K+ pump, Action potentials, saltatory conduction (with myelin sheath), and synapses)
- Muscle Function (actin & myosin, tropomyosin & troponin, & sarcoplasmic reticulum)
Raven's Animation:
- Phytochromes (Pr and Pfr) (McGraw Hill animation) or at Youtube
- Pearson's Animation of (1) The neuromuscular junction, (2) the Excitation of the Muscle Fiber and (3) The Cross Bridge Cycle
- Crash Course in Big Guns: Muscle System (somewhat enetertaining and educational)

History: Recording an Action Poential by Hodgkin; Squid Axon Nerve Removal (MIT)
ahn Academy can lecture you about
- The Nervous System (neurons, the Na+/K+ pump, Action potentials, saltatory conduction (with myelin sheath), and synapses)
- Muscle Function (actin & myosin, tropomyosin & troponin, & sarcoplasmic reticulum)
Raven's Animation:
- Phytochromes (Pr and Pfr) (McGraw Hill animation) or at Youtube
- Pearson's Animation of (1) The neuromuscular junction, (2) the Excitation of the Muscle Fiber and (3) The Cross Bridge Cycle
- Crash Course in Big Guns: Muscle System (somewhat enetertaining and educational)
Mr. Anderson will continue to walk you thorugh the last topics of the year:
- Behavior & Natural Selection
- Response to External Environments - Address hibernation & Migration & Temperature control
- Cellular Cooperation (Bozeman)
- Abiotic & Biotic Factors- distinctions
- Populations (& Communities)
- Exponential Growth (Equations) & Logistic Growth (Equations)
- Population Modeling in Spreadsheets
- Communities and Ecological Succession
- Biodiversity
- Ecosystems & Populations Food Chains, Primary Productivity, Logistic Growth
- Ecosystem Change
- Homeostatic Disruptions - Includes Brown Tree Snake

Kristina Gremski tries her hand with
Energy Transfer in Ecosystems - Food Chains
Water & Carbon cycles
Nitrogen & Phosphorus cycles

Harvard's Invasive Species Tutorial
Marmosets learn by watching one another (J. Nature)

 UNIT #12

 REVIEW FOR THE AP BIOLOGY TEST - Separate Binder of Pages

Week 33: April 27 - May 1 (MON.- LAST DAY FOR SENIORS; MAY PROJECTS BEGIN AP exams; Revew handouts coming; tues - no school)
Class 1

Discuss test structure
Review Statistics and practice problems
Collect 2018 Practice Exam Scantron & Grid page

Do the 2018 Practice Exam (Review Binder pages 109-168 multiple choice and calculation problems only). You may use resources if necessary to determine your answers. Write your answers on a scantron; put the calculation answers on the grid sheet. Here is the look of the AP Bio Test Booklet (2013)
Of possible value: Try Virtual labs for review

Lab 1

No School; Break


Do the 2017 Practice Exam (Review Book pages 169 - 227; ; multiple choice AND calculation problems) Write your answers on a scantron & grid sheet.
Class 2

Handback 2018 Practice Exam; Collect the 2017 and 2016 Practice Exam Scantrons and Grid Pages
Review the Calculation problems
Do a couple Data Analysis Practice (Binder pg. 11 - 14)
Round Robin FRQs (5 Questions) - Whiteboards
Start Calculation Review Problems (Binder 15 - 24)

Meeting Time:

Do the 2016 Practice Exam (review Book pages 228-280; multiple choice AND calculation problems) Write your answers on a scantron & grid sheet.
Lab 2

Hand back the 2016 & 2015 Practice Exams
Review the Calculation problems of the 2016 & 2015 Exam
Complete the Calculation Review Problems (Binder 27 - 36)
AP Bio Lab Review

Meeting Time:



Do the following:
Finish any AP Bio Practice tests that you haven't yet finished.

Come with a list of topics that you are least sure of. Go through your text book, your notes, your lab manual, your binders. What do you remember the least?

Write the list down and give it to me tomorrow. I'll use it to plan the things we will cover on Friday.

Class 3

AP Bio Lab Review
Review - Topics - Student Choice
Details of the exam; what to bring to exam

Meeting Time:

Do the 2019 Practice Exam ALONE, NO RESOURCES & TIMED, 90 minutes!! (review Book pages 65 - 108; multiple choice AND calculation problems; not the essays) Write your answers on a scantron & grid page.
Be Hardcore Bio

Check out some of the review videos below. Try any remaining AP Exams I have given you. Study with a friend; ask one another questions. Sleep well Sunday night! Look at the remaining AP Bio Tests (answers will be distributed)

Review Resources Mr. Anderson goes over the new AP labs (Part 1 and Part 2)
Mr. Anderson reviews: Homeostasis, Natural Selection, Speciation, Cell Communication,
Some Free AP Bio Review Questions at https://www.learnerator.com (can also purchase an upgrade) and their new (2016) upgrade: https://www.albert.io/ap-biology
Math Bench - Biology Modules
Mr. Knuffle's Review Powerpoints - Nice Syntheses: Evolution, Matter, Energy, Information, Regulation, Communication, Interactions
Week 34: May 4 - 8 (Bahe at Biology DreYland) - Prepare on your own

Week 35: May 11 AP Bio test has finally arrived!!

Mon., May 11

7:45 am -- in the ?????????? Room (probably MultiPurpose Room)
Be on time - in fact, BE EARLY!! Bring pencils, pens and a watch!! Bring a good calculator and extra batteries. Bring a snack for the break time.
Good Luck!!